Journal Articles | murarka-lab

2024

49. Photoredox-Catalyzed Arylative and Aryl Sulfonylative Radical Cascades Involving Diaryliodonium Reagents: Synthesis of Functionalized Pyrazolones.

K. R. Thombare, S. K. Parida, P. Meher, and S. Murarka*

Chem. Commun, 2024, 60, 13907-13910 . Published as part of ChemCommun Emerging Investigator Collection 2024.

WhatsApp Image 2024-10-31 at 13.35.26.jpeg

45. Cost-Effective Carbon Quaternization with Redox-Active Esters and Olefins.

S.K. Hota and S. Murarka*

Angew. Chem. Int. Ed. 2024, e202408301.

46. Electrochemical C-H Alkylation of Azauracils Using N-(Acyloxy)phthalimides.

R. Dash, S. P. Panda, K. S. Bhati, S. Sharma,* and S. Murarka*

Org. Lett. 2024, 26, 7227-7232.

48. Copper-Photoredox-Catalyzed Divergent Strategy for the Site-selective Arylation and Alkylation of Glycines and peptides.

P. Meher, M. S. Prasad, K. R. Thombare, and S. Murarka*

ChemRxiv, 2024, doi.10.26434/chemrxiv-2024-hf343 .

WhatsApp Image 2024-09-16 at 15.15.24.jpeg

47. C-H alkylation of heterocycles via light-mediated palladium catalysis.

S. Senapati, S. K. Hota, L. Kloene, C. Empel,* S. Murarka*, and R. M. Koenigs*

Angew. Chem. Int. Ed. 2024, doi.org/10.1002/anie.202417107. Previously in ChemRxiv Preprint, 2024, doi.10.26434/chemrxiv-2024-2v39h.

43. Visible Light-Mediated Difluoromethylation/Cyclization in Batch and Flow: Scalable Synthesis of CHF2- Containing Benzimidazo- and Indolo[2,1-a]isoquinolin-6(5H)-ones.

A. Hannam,+ P. Kankraisri,+ K. R. Thombare,+ P. Meher, A. Jean, S. T. Hilton, S. Murarka,* and S. Arseniyadis*

Chem. Commun. 2024, 60, 7938-7941.

+these three authors contributed equally to this work.

WhatsApp Image 2024-07-03 at 21.51.19.jpeg

44. Overriding Cage Effect in Electron Donor-Acceptor Photoactivation of Diaryliodonium Reagents: Synthesis of Chalcogenides.

P. Meher, S. K. Parida, S. K. Mahaptra, L. Roy,* and S. Murarka*

Chem. Eur. J. 2024, doi.org/10.1002/chem.202402969. Previously in ChemRxiv Preprint 2024, doi.10.26434/chemrxiv-2024-xfssk .

WhatsApp Image 2024-07-09 at 13.18.03.jpeg

39. Base-Promoted 1,6-Aza-Michael Addition of Azauracils to para-Quinone Methides.

R. Dash,+ S. K. Hota,+ and S. Murarka*

Synthesis. 2024, 56, 677-685. Invited for the special collection on "Synthetic Development of Key Intermediates and Active Pharmaceutical Ingredients (APIs)."

+these two authors contributed equally to this work.

40. Visible Light Induced Imide Alkylation of Azauracils with Aryl Diazoesters.

S. K. Hota and S. Murarka*

Chem. Asian J. 2024, doi.org/10.1002/asia.202301027. Invited for the special collection on Early Career Researcher.

2023

38. A General Electron Donor–Acceptor Photoactivation Platform of Diaryliodonium Reagents: Arylation of Heterocycles.

P. Meher, S. P. Panda,+ S. K. Mahapatra,+ K. R. Thombare, L. Roy* and S. Murarka*

Org. Lett. 2023, 25, 8290–8295. One of the Most Read Article in November 2023.

+these two authors contributed equally to this work.

37. Organophotoredox-Catalyzed Arylation and Aryl Sulfonylation of Morita-Baylis-Hillman Acetates with Diaryliodonium Reagents.

S. Senapati,+ S. K. Parida,+ S. S. Karandikar and S. Murarka*

Org. Lett. 2023, 25, 7900-7905.

+these two authors contributed equally to this work.

36. Copper-catalyzed tandem cyclization/arylation of α,β-alkynic hydrazones with diaryliodonium salts: synthesis of N-arylpyrazoles.

S. K. Parida, S. Joshi and S. Murarka*

Org. Biomol. Chem. 2023, 21, 5784. Invited for the special collection on RSC-IIT Roorkee@CFOS conference.

42. Direct C-H Alkylation of 3,4-Dihydroquinoxaline-2-ones with N-(acyloxy)phthalimides via Radical-Radical Cross Coupling.

S. K. Hota, G. Singh, and S. Murarka*

Chem. Commun. 2024, 60, 6268-6271. One of the top 20% most downloaded ChemComm publications during June and July.

41. Photodecarboxylative Radical Cascade Involving N-(Acyloxy)phthalimides for the Synthesis of Pyrazolones.

S. P. Panda, R. Dash, S. K. Hota, and S. Murarka*

Org. Lett. 2024, 26, 3667–3672. Published as part of Organic Letters virtual special issue “Radical Reactions for the Construction and Transformation of Complex Molecules”.

35. Photodecarboxylative C−H Alkylation of Azauracils with N‑(Acyloxy)phthalimides.

S. P. Panda,+ S. K. Hota,+ R. Dash, L. Roy, and S. Murarka*

Org. Lett. 2023, 25, 3739-3744. Highlighted on Organic Chemistry Portal. See here: https://www.organic- chemistry.org/abstracts/lit9/032.shtm.

+these two authors contributed equally to this work.

33. Photoinduced Electron Donor-Acceptor Complex-Mediated Radical Cascade Involving N-

(Acyloxy)phthalimides: Synthesis of Tetrahydroquinolines.

S. K. Hota,+ S. P. Panda,+ S. Das, S. K. Mahapatra, L. Roy*, S. De Sarkar* and S. Murarka*

J. Org. Chem. 2023, 88, 2543. One of the Most Read Article in February 2023.

+these two authors contributed equally to this work.

34. Visible light photoredox-catalyzed arylative cyclization to access benzimidazo[2,1-a]isoquinolin-6(5H)-ones.

P. Meher, R. K. Samanta, S. Manna and S. Murarka*

Chem. Commun. 2023, 59, 6092-6095.

2021

29. An organophotoredox-catalyzed redox-neutral cascade involving N-(acyloxy)phthalimides and allenamides: synthesis of indoles,

S. Das,+ A. Azim,+ S. K. Hota, S. P. Panda, S. Murarka*, S. De Sarkar*

Chem. Commun. 2021, 57, 13130. +these two authors contributed equally to this work. Invited for the

special issue on Functionalization of unreactive C-H bonds.

28. Multicomponent Synthesis of Biologically Relevant S-Aryl Dithiocarbamates Using Diaryliodonium Salts,

S. K. Parida, S. Jaiswal, P. Singh*, S. Murarka*

Org. Lett. 2021, 23, 6401. Highlighted on Organic Chemistry Portal. See here: https://www.organic-

chemistry.org/abstracts/lit8/091.shtm.

27. Organophotoredox-Catalyzed Late-Stage Functionalization of Heterocycles,

S. K. Hota,+ D. Jinan,+ S. P. Panda, R. Pan, B. Sahoo*, S. Murarka*

Asian J. Org. Chem. 2021, 10, 1848. Selected for the cover page. +these two authors contributed equally.

Invited for the special issue on Organocatalysis. Top Cited Article during 2021-2022.

26. Late-Stage Alkylation of Heterocycles Using N-(Acyloxy)phthalimides,

S. K. Parida,+ S. K. Hota,+ R. Kumar, S. Murarka*

Chem. Asian J. 2021, 16, 879. +these two authors contributed equally to this work.

Top Downloaded Article during 2021-2022.

25. Organophotoredox-catalyzed redox-neutral cascade involving N-(acyloxy)phthalimides and maleimides,

S. Das, S. K. Parida+, T. Mandal+, S. K. Hota, S. De Sarkar*, S. Murarka*

Org. Chem. Front. 2021, 8, 2256. +these two authors contributed equally to this work. Invited Contribution.

24. Single Electron Transfer-Induced Redox Processes Involving N-(Acyloxy)phthalimides,

S. K. Parida+, T. Mandal+, S. Das, S. K. Hota, S. De Sarkar*, S. Murarka*

ACS Catal. 2021, 11, 1640. +these two authors contributed equally to this work.

Bioorganic & Medicinal Chemistry cover.jpg

2022

32. Visible Light Photoredox-Catalyzed Direct C–H Arylation of Quinoxalin-2(1H)-ones with Diaryliodonium Salts,

R. K. Samanta,+ P. Meher,+ S. Murarka*

J. Org. Chem. 2022, 87, 10947. One of the Most Read Article in August 2022. Highlighted on Organic

Chemistry Portal. See here: https://www.organic-chemistry.org/abstracts/lit8/590.shtm.

+these two authors contributed equally to this work.

31. Development of S-aryl dithiocarbamate derived novel antiproliferative compound exhibiting tubulin bundling,

S. Jaiswal,+ S. Parida,+ S. Murarka*, P. Singh*

Biorg. Med. Chem. 2022, 68, 116874.

+these two authors contributed equally to this work.

30. Multicomponent Synthesis of Biologically Relevant S-Diarylmethane Dithiocarbamates Using p-Quinone

Methides,

S. Parida,+ S. K. Hota,+ S. Jaiswal, P. Singh*, S. Murarka*

Adv. Synth. Catal. 2022, 364, 1549. Selected as a Very Important Publication (VIP).

+these two authors contributed equally to this work.

2020

23. Organophotoredox Catalyzed Cascade Radical Annulation of 2-(Allyloxy)arylaldehydes with N-

(acyloxy)phthalimides: Towards Alkylated Chroman-4-one Derivatives,

S. Das, S. K. Parida+, T. Mandal+, L. Sing, S. De Sarkar*, S. Murarka*,

Chem. Asian J. 2020, 15, 568. +these two authors contributed equally to this work. Invited for the special issue on International Conference on Organometallics and Catalysis 2020 (ICOC-II).

2019

22. Late Stage Functionalization of Heterocycles Using Hypervalent Iodine(III) Reagents,

R. Budhwan, S. Yadav, S. Murarka*,

Org. Biomol. Chem. 2019,17, 6326-6341. Invited for the special issue on C-H Activation

in Late Stage Functionalization.

21. PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRas,

C. H. Klein, D. C. Truxius, H. A. Vogel, J. Harizanova, S. Murarka, P. Martín-Gago, P. I. Bastiaens,

Int. J. Cancer 2019,144, 767.

2018

20. Metal Catalyzed Oxidative Coupling of Ketones and Ketone Enolates,

S. Murarka*, A. P. Antonchick*,

Synthesis 2018, 50, 2150. Invited Contribution.

19. N-(acyloxy)phthalimides as Redox-Active Esters in Cross Coupling Reactions,

S. Murarka*,

Adv. Synth. Catal. 2018, 360, 1735.

Selected as "very important publication" (VIP)

One of Top 20 most downloaded articles in the past 12 months

2017

18. Biology-Oriented Synthesis of Decahydro-4,8-epoxyazulene Scaffolds,

Z-J. Jia, C. Merten, L. Knauer, S. Murarka, C. Strohmann, H. Waldmann,

Synlett 2017, 28, 2918.

17. Covalent Protein Labelling at Glutamic Acids,

P. Martín-Gago, E. K. Fansa, M. Winzker, S. Murarka, P. Janning, A. Wittinghofer, H. Waldmann,

Cell Chem. Biol. 2017, 24, 589.

16. A PDE6δ-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2,

P. Martín-Gago,# E. K. Fansa,# C. H. Klein,# S. Murarka,# P. Janning, M. Schürmann, M. Metz, S. Ismail, C. Schultz-Fademrecht, M. Baumann, P. I. Bastiaens, A. Wittinghofer, H. Waldmann,

Angew. Chem. Int. Ed. 2017, 56, 2423. #these authors contributed equally to this work.

15. Development of Pyridazinone Chemotypes Targeting the PDEδ Prenyl Binding Site,

S. Murarka,# P. Martín-Gago,# C. Schultz-Fademrecht, A. A. Saabi, M. Baumann, E. K. Fansa, S. Ismail, P. Nussbaumer, A. Wittinghofer, H. Waldmann,

Chem. Eur. J. 2017, 23, 6083. #these two authors contributed equally to this work.

14. Biology-Oriented Synthesis of 3,3-Spiro (2-tetrahydrofuranyl)-oxindoles,

S. Murarka, C. Golz, C. Strohmann, A. P. Antonchick and H. Waldmann,

Synthesis 2017, 49, 87. (invited contribution).

2016

13. Identification of a Pyrazolopyridazinones as KRas-PDEδ Inhibitors,

B. Papke,# S. Murarka,# H. A. Vogel,# P. Martín-Gago,# D. C Truxius, M. Kovacevic, E. K. Fansa, S. Ismail, G. Zimmermann, K. Heinelt, C. Schultz-Fademrecht, A. A. Saabi, M. Baumann, P. Nussbaumer, A. Wittinghofer, H. Waldmann, P. I. Bastiaens,

Nat. Commun. 2016, 7,11360. #these authors contributed equally.

2015

12. Rhodium(II) Catalyzed Enantioselective Synthesis of Troponoids,

S. Murarka, Z-J. Jia, C. Merten, C-G. Daniliuc, A. P. Antonchick and H. Waldmann,

Angew. Chem. Int. Ed. 2015, 54, 7653.

Highlighted in Nachrichten aus der Chemie 2015, 63, 875.

Highlighted in Synfacts 2015, 0824.

11. TEMPO-Mediated Homocoupling of Aryl Grignard Reagents: Mechanistic Studies, S. Murarka, J. Möbus, G. Erker, C. Mück-Lichtenfeld and A. Studer, Org. Biomol. Chem. 2015, 13, 2762.

2014-2009

10. Structure Guided Design and Kinetic Analysis of Highly Potent Benzimidazole Inhibitors Targeting the PDEδ Prenyl Binding Site,

G. Zimmermann, C. Fademrecht, P. Küchler, S. Murarka, S. Ismail, G. Triola, P. Nussbaumer, A. Wittinghofer, and H. Waldmann,

J. Med. Chem. 2014, 57, 5435.

9. Phenyl Hydrazine as Initiator for Direct Arene C–H Arylation via Base Promoted Homolytic Aromatic Substitution,

A. Dewanji, S. Murarka, D. Curran and A. Studer,

Org. Lett. 2013, 15, 6102.

8. Radical/Anionic SRN1-Type Polymerization for Preparation of Oligoarenes,

S. Murarka and A. Studer,

Angew. Chem. Int. Ed. 2012, 51, 12362. Selected as “Hot Paper”. Highlighted in Synfacts 2013, 0154. Reported in C&EN news, 90(46), November 12, 2012.

7. Transition-Metal-Free Oxidative Coupling Reactions for the Formation of C–C and C–N Bonds Mediated by TEMPO and its Derivatives,

S. Murarka, S. Wertz and A. Studer,

Chimia. 2012, 66, 413.

6. Transition-Metal-Free TEMPO Catalyzed Oxidative Cross Coupling of Nitrones with Alkynyl Grignard Reagents,

S. Murarka and A. Studer,

Adv. Synth. Cat. 2011, 353, 2708.

5. Zinc Triflate Catalyzed Aerobic Cross-Dehydrogenative Coupling (CDC) of Alkynes with Nitrones: a New Entry to Isoxazoles,

S. Murarka and A. Studer,

Org. Lett. 2011, 13, 2746.

4. Transition-Metal-Free Sonogashira-type Coupling of ortho-Substituted Aryl and Alkynyl Grignard Reagents by Using 2,2,6,6-Tetramethylpiperidine-N-oxyl Radical (TEMPO) as an Oxidant,

M. S. Maji, S. Murarka and A. Studer,

Org. Lett. 2010, 12, 3878. Highlighted in Synfacts 2010, 1401.

3. Catalytic Enantioselective Intramolecular Redox Reactions: Ring-Fused Tetrahydroquinolines,

S. Murarka, I. Deb, C. Zhang and D. Seidel,

J. Am. Chem. Soc. 2009, 131, 13226. Highlighted in Synfacts 2009, 1352.

Highlighted in SYNFORM 2009/09, A76.

2. Lewis Acid Catalyzed Formation of Tetrahydroquinolines via an Intramolecular Redox Process,

S. Murarka, C. Zhang, M. D. Konieczynska and D. Seidel,

Org. Lett. 2009, 11, 129. Highlighted in Synfacts 2009, 367.

1. Facile Formation of Cyclic Aminals Through A Brønsted Acid Promoted Redox Process,

C. Zhang, S. Murarka, D. Seidel,

J. Org. Chem. 2009, 74, 419.